FPV-FCOV-GIA Ag Rapid Test
One Card, Three Tests – Accurately Target the Three Most Common Causes of Diarrhea
Feline diarrhea is a common clinical symptom with diverse causes, among which Feline Panleukopenia Virus (FPV), Feline Enteric Coronavirus (FCoV), and Giardia are three core pathogens. This product utilizes multiplex immunochromatographic technology to simultaneously, rapidly, and qualitatively detect FPV antigen, FCoV antigen, and Giardia antigen in feline fecal samples. This integrated design enables one-time differentiation between viral enteritis and parasitic enteritis, providing immediate, crucial laboratory evidence for developing precise treatment plans (antiviral, supportive therapy, or deworming).
I. Core Value and Clinical Application
Efficient Etiological Differential Diagnosis: Diarrhea caused by FPV (highly lethal virus), FCoV (common enteric virus), and Giardia (zoonotic parasite) may present with similar initial symptoms, yet require entirely different treatment approaches. This triple test card quickly distinguishes the cause into life-threatening infectious disease, self-limiting/monitorable viral infection, or parasitic disease requiring specific deworming, preventing misdiagnosis and treatment delays.
Guide Emergency Intervention and Targeted Medication:
FPV Positive: Immediate isolation, intensive supportive treatment, and close monitoring are required.
FCoV Positive: Usually managed with symptomatic support, and indicates a need for monitoring future health (serving as an indirect reference for FIP risk assessment).
Giardia Positive: Requires specific deworming medications (e.g., metronidazole, fenbendazole) and thorough environmental cleaning and disinfection to prevent recurrence and transmission.
Enhance Management Efficiency in Multi-Cat Environments: One single test can screen for three pathogens significantly impacting group health, making it particularly suitable for new cat intake quarantine checks, diarrhea outbreak investigations in catteries/rescue centers, and routine health monitoring, facilitating rapid implementation of group control measures.
Convenient Operation, Rapid Results: A single fecal sample, one simple procedure, delivers three results in about 10-15 minutes, greatly optimizing clinical workflow.
II. Test Items, Markers, and Key Interpretation
| Test Item | Detection Marker | Core Interpretation of Positive Result and Clinical Significance |
|---|---|---|
| Feline Panleukopenia Virus (FPV) | Viral Antigen (Ag) | Indicates active FPV infection. Combined with clinical symptoms (high fever, vomiting, leukopenia), it holds high diagnostic value and necessitates immediate emergency medical response. |
| Feline Coronavirus (FCoV) | Viral Antigen (Ag) | Indicates FCoV replication and shedding in the intestines. Important Note: A positive result only signifies enteric infection and must NOT be directly diagnosed as Feline Infectious Peritonitis (FIP). Comprehensive evaluation with other indicators is required. |
| Giardia(GIA) | Parasite Antigen (Ag) | Indicates active Giardia infection. A positive result supports the use of specific deworming treatment and signals a public health risk, necessitating proper environmental and personal hygiene measures. |
III. Operation and Result Interpretation
Simple Procedure:
Sampling: Use the provided swab to collect a fresh feline fecal sample or rectal swab.
Processing: Place the swab into the sample tube containing diluent, stir and squeeze thoroughly to mix.
Testing: Using a dropper, aspirate the supernatant and vertically add 3-4 drops to the test card sample well (S well).
Interpretation: Observe the results under adequate light within 10-15 minutes. The Control line (C) must be visible for the test to be valid.
Result Interpretation (Each test line is clearly labeled):
Triple Negative: Only the Control line (C) is visible; all three test lines (FPV, FCoV, Giardia) are not visible.
Single Positive: The C line is visible, and the corresponding single test line is visible.
Multiple Positive: The C line is visible, and two or three test lines are simultaneously visible (e.g., FCoV and Giardia double positive suggests mixed infection).
Invalid: The Control line (C) is not visible; retest with a new device.
IV. Important Clinical Notes and Limitations
Auxiliary Diagnostic Role:
FPV: While a positive result is highly significant, confirmation should still be combined with blood tests (characteristic severe leukopenia is typical).
FCoV: It must be strongly emphasized that fecal antigen positivity has no direct causal relationship with FIP. FIP diagnosis is a complex clinical synthesis and cannot be determined by this test alone.
Giardia: Cyst shedding is intermittent. A single negative result cannot completely rule out infection. For highly suspected cases with negative results, testing for 3 consecutive days or PCR testing is recommended.
Vaccination Interference: Testing within days after FPV vaccination (modified live vaccine) may cause transient positive FPV antigen detection due to vaccine strain shedding.
Sample Quality and Window Period: Use fresh fecal samples (best within 4 hours). In very early infection, antigen load may be below the detection limit, leading to false negatives.
Does Not Cover All Diarrhea Etiologies: This test does not cover other common pathogens such as feline calicivirus, bacterial enteritis (e.g., Campylobacter), or other parasites (e.g., coccidia, Tritrichomonas foetus). If symptoms persist with a triple negative result, expand the diagnostic scope.
V. Storage and Specifications
Storage Conditions: Store sealed at 2-30°C in a cool, dry place. Do not freeze.
Shelf Life: 24 months.
Packaging: Individual foil pouches, 10 tests per box.